New antiobesity gene discovered

12 10 2007

A new research has revealed an antiobesity gene that keeps worms and mice trim, according to a study published in the journal Cell Metabolism. If the gene works similarly in humans, the findings could lead to a new weapon against obesity.

The research has shown how animals without a working copy of the gene, known as Adipose (Adp), become obese and resistant to insulin, while those with increased Adp activity in fat tissue become slimmer. During the study, researchers used a treatment that increased Adp in the animals’ fat tissue, leding them to lose weight.

While fat storage is an important mechanism for getting through lean times, too much fat in times of plenty has deleterious consequences. In a modern world where many people have essentially unlimited access to food, it’s a wonder that even more people aren’t overweight. If this gene plays a similar role in humans it might mean that those with a high food intake but still lean, Adp would work well, while in those who are fat would’t be working properly.

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2 responses

12 11 2007
Adak

If the gene works similarly in humans, the findings could lead to a new weapon against obesity.

No thank you. Even if my genes make me fat I prefer to be 100% human, not 0.001% mouse 🙂

24 11 2007
Joan

That’s only if there’s a similar gene found in humans, it doesn’t mean that they would insert the mouse gene in the human genome.
Anyways, you share a great percentage of your genome with mice… so, in that way you are more than 0.001% mouse 😉

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